Searchable abstracts of presentations at key conferences on calcified tissues

ba0002oc24 | Miscellaneous | ICCBH2013

Fibroblast Growth Factor 23 Plasma Levels Are Elevated with Early Chronic Kidney Disease and Positively Associated with Steroid Based vs Steroid Free Immunosuppression in Pediatric Renal Transplant Patients

Srivastava Rachana , Srivaths Poyyapakkam , Brewer Eillen

Background: Fibroblast growth factor 23 (FGF23) is a circulating phosphaturic hormone that also suppresses renal 1α-hydroxylase activity. In adult patients (pts) plasma FGF23 increases in early stages of chronic kidney disease (CKD), even before serum phosphorus changes. In a study of 984 adult renal transplant pts, higher FGF23 levels were independently associated with increased risk of all-cause mortality and allograft loss during 39 months follow-up2</sup...